HUMAN HEALTH RISK ASSESSMENT OF ORGANOCHLORINE COMPOUNDS ASSOCIATED WITH RAW MILK CONSUMPTION IN A ROMANIAN INDUSTRIAL AREA

Main Article Content

M. MICLEAN
O. CADAR
E.A. LEVEI
D.A. TODEA

Keywords

health risk assessment, OCPs, PCBs, raw milk

Abstract

Dietary exposure to organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), generically named organochlorine compounds (OCCs) represents nowadays an important health risk for humans, due to their endocrine-disrupting and carcinogenic effects. In order to assess the potential health risk associated with raw milk consumption 10 milk samples were collected from a local market in Baia-Mare industrial area, Romania. The concentrations of OCPs and PCB congeners in these samples were determined by capillary gas chromatography with electron-capture detection, after liquid-liquid extraction. In all samples, the OCCs were below the maximum admitted concentrations set by European legislation. The most predominant compounds were 4,4’-DDE (11.5 ng/g lipid wt.), B-HCH (10.1 ng/g lipid wt.) and PCB180 (5.08 ng/g lipid wt.). Exposure assessment through milk consumption was performed for male, female and children, by calculating the estimated daily intakes (EDIs) and the hazard indices (HIs) for non-carcinogenic effects. The obtained EDIs were lower than the acceptable daily intake values and HIs were far below 1, indicating no potential health risk for the investigated population.

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