ANTIOXIDANT AND ANTI-INFLAMMATORY CAPACITIES OF PEPPER TISSUES

Main Article Content

G.H. QIAO
D. WENXIN
X. ZHIGANG
R. SAMI
E. KHOJAH
S. AMANULLAH

Keywords

pepper, antioxidant, anti-inflammatory, cell line

Abstract

The objective of this study was to investigate the antioxidant and anti-inflammatory activities of five pepper varieties tissues. Green Bell peppers had the highest total antioxidant contents; while Red Chilli variety had the lowest antioxidant activities (ABTS was 3.89 ?mol TE/g fw, DPPH was 2.82 ?mol TE/g fw and FRAP was 16.95 ?mol TE/g fw). The methanolic extracts of different peppers showed strong but different anti-inflammatory activity values (8.22 ?g/ml - 9.52 ?g). Yellow Bell, Red and Green Chilli had the highest anti-inflammatory activity followed by Green and Red Bell extracts, respectively. The results suggest that these varieties of pepper could contribute as sources of important antioxidant and anti-inflammatory related to the oxidative stress and inflammation prevention.

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References

Alet V.T., Annie M.J.and Duncan C.A. 2015. Limitations of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay when compared to three commonly used cell enumeration assays. BMC Res Notes. 8(47):1-10.

Allemand A., Leonardi B.F., Zimmer A.R., Moreno S., Romão P.R. and Gosmann G. 2016. Red pepper (Capsicum baccatum)extracts present anti-inflammatory effects in vivo and inhibit the production of TNF-?and NO in vitro. Journal of Medicinal Food19(8):759-767.

Alvarez-Parrilla E., Laura A., Amarowicz R. and Shahidi F. 2012. Protective effect of fresh and processed Jalapeas and Serrano peppers against food lipid and human LDL cholesterol oxidation. Food Chemistry 133:827-834.

Aminifard M.H., Aroiee H., Nemati H., M.Aziziand Jaafar H.Z. 2012. Fulvic acid affects pepper antioxidant activity and fruit quality. African Journal of Biotechnology 11(68):13179-13185.

Anna K., Ulvi M., Mari S.and Reijo K. 2014. The impact of harvesting, storage and processing factors on health-promoting phytochemicals in berries and fruits. Processes 2:596-624.

Hamidreza J., Esmaeil M., Zeinab P., Gert F., Mehrnaz M., Milad M., Ian M. and Johan G. 2017. Nitric oxide in the pathogenesis and treatment of tuberculosis. Front Microbiol. 8:1-11.

Ilahy R., Hdider C., Lenucci M.S., Tlili I. and Dalessandro D. 2011. Antioxidant activity and bioactive compound changes during fruit ripening of high-lycopene tomato cultivars. Journal of Food Composition and Analysis 24:588-595.

Kaur C., Walia S., Nagal S., Walia S., Singh J., Singh B.B., Saha S., Singh B., Kalia P.and Jaggi S. 2013. Functional quality and antioxidant composition of selected tomato (Solanum lycopersicon L) cultivars grown in Northern India LWT -Food Science and Technology 50:139-145.

KimH G., Bae H. and JastrzebskiZ. 2016. Binding, antioxidant and anti-proliferative properties of bioactive compounds of sweet paprika (Capsicum annuumL.).Plant Foods for Human Nutrition 71(2):129-136.

Lonkar P. and Dedon P.C. 2011. Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates. International Journal of Cancer 128:1999-2009.

Magalhaes L.M., Segundo M.A., Reis S. and Lima J. 2008. Methodological aspects about in vitro evaluation of antioxidant properties. Analytica Chimica Acta 613(1):1-19.

Montecucco, F., Pende, A., Quercioli, A. and Mach F.2011, Inflammation in the pathophysiology of essential hypertension. Journal of Nephrology24:23-24

Nimmakayala, P., Abburi V.L. and Saminathan T. 2016. Genome-wide divergence and linkage disequilibrium analyses for Capsicum baccatum revealed by genome-anchored single nucleotide polymorphisms. Frontiers in Plant Science 7(1646):1-12.

Prasad N., Yang B., Kong K.W., Khoo H.E., Sun J., Azlan A., Ismail A. and Romli Z.B. 2013. Phytochemicals and antioxidant capacity from nypafruticanswurmb. fruit. Evidence-Based Complementary and Alternative Medicine 154606:1-9.

Rahim R.A. and Mat I. 2012. Phytochemical contents of capsicum frutescens (Chili Padi), capsicum annum (Chili Pepper) and capsicum annum (Bell Peper) aqueous extracts. International Conference on Biological and Life Sciences 40:164-167.

Rokayya S., Garsa A., Ying M., Amro A. and Nada B. 2019. Evaluation of some specific components existences in Okra (Abelmoschus Esculentus L. (Moench)) cultivated from different areas. Journal of Food and Nutrition Research 7(2):155-161.

Shumaila J., Muhammad R., Umbreen R.and Jasia B. 2013. Assessment of antioxidant potential, total phenolics and flavonoids of different solvent fractions of monotheca buxifolia fruit public health res perspect. Puplic Health 4(5):246-254.

Silva L.R., Azevedo J., PereiraM.J., Carro L., Veláque E., Pei A.P. and AndradeP.B., 2014a. Inoculation of the nonlegume capsicum annuum l. with rhizobium strains. 2. Changes in sterols, triterpenes, fatty acids, and volatile compounds. Journal of Agriculture and Food Chemistry 62:565-573.

Silva L.R., Azevedo J., Pereira M.J., CarroL., Velázquez E., Pei A.P.and Andrade, P.B. 2014b. Inoculation of the nonlegume capsicum annuum (l.) with rhizobium strains.1. Effect on bioactive compounds, antioxidant activity, and fruit ripeness. Journal of Agriculture and Food Chemistry 62, 557-564.

Silva L.R., Azevedo J., Pereira M.J., Valentão P., and Andrade P.B., 2013. Chemical assessment and antioxidant capacity of pepper (Capsicum annuum L.) seeds. Food and Chemical Toxicology 53, 240-248.

Sung J., Jeong H.S. and Lee J. 2016. Effect of the capsicoside G-rich fraction from pepper (Capsicum annuum L.)seeds on high-fat diet-induced obesity in mice. Phytotherapy Research30 (11):1848-1855.

Suresh K. and Priya K. 2015. Antiproliferative activity and nitric oxide production of a methanolic extract of Fraxinus micranthaon michigan cancer foundation-7 mammalian breast carcinoma cell line. J. Intercult Ethnopharmacol 4(2):109-113.

Young-Jun L., Dan-Bi K., Jong S.L., Ju-Hyun C., BongK.K, Hyeon-Son C., Boo-Yong L.and Ok-Hwan L. 2013. Antioxidant activity and anti-adipogenic effects of wild herbs mainly cultivated in Korea. Molecules 18(10):12937-12950.

Zimmer A.R., Leonardi B., Miron D., Schapoval E., Oliveira J.R. and Gosmann G. 2012. Antioxidant and anti-inflammatory properties of capsicum baccatum: from traditional use to scientific approach. Journal of Ethnopharmacology 139(1):228-233.